WebThere are 6 disease interactions with cyclophosphamide. Myelosuppression Urinary tract obstruction Cardiac disease/cardiotoxicity Hepatic dysfunction Pulmonary impairment Renal dysfunction Major Cyclophosphamide (applies to cyclophosphamide) myelosuppression Major Potential Hazard, High plausibility. WebFeb 7, 2024 · The clinical features of fatal cyclophosphamide-induced cardiotoxicity in a conditioning regimen for allogeneic hematopoietic stem cell transplantation (allo-HSCT). Ann Hematol 2016; 95(7): 1145–1150. Crossref. PubMed. Google Scholar. 35. Duléry R, Mohty R, Labopin M, et al. Early cardiac toxicity associated with post-transplant ...
Chemotherapie in der Schwangerschaft SpringerLink
WebApr 11, 2024 · Cardiotoxicity means permanent damage to the muscles of the heart or the functioning of the heart. Cardiotoxicity can be severe with Adriamycin treatment and may develop late during therapy, or within two to three months after the treatment has ended. WebJan 10, 2024 · Cyclophosphamide is a prodrug that requires an activation step by cytochromes (P450) in the liver [ 14 ]. As shown in Figure 1, the introduction of the hydroxyl group to the oxazaphosphorine ring … いい匂いがする 英語で
Role of metabolites of cyclophosphamide in cardiotoxicity
WebFeb 1, 2024 · Cyclophosphamide and cardiotoxicity Cyclophosphamide is one of the potent alkylating agents used widely against rheumatoid arthritis, lupus erythematosus, … WebApr 15, 2024 · In a retrospective analysis of 102 patients, et al. patient support program conducted between January 2011 and December 2012, 11 patients [1 woman; not all sexes stated] aged 38−62 years were described, who developed ejection fraction (EF) decreased or ventricular ectopic, manifested as cardiac toxicity, following the therapy with … WebDec 19, 2024 · Cyclophosphamide is an alkylating agent that is used for a variety of malignancies, including breast cancer, lung cancer, lymphomas, and in conditioning regimens before stem cell transplantation. High-dose cyclophosphamide (>1.5 g/m 2 /day) is considered to be highly cardiotoxic, with CTRCD incidences ranging from 7% to 28% ( … いい匂い シャンプー 男 市販